120kgDry granulation of traditional Chinese medicine spray-dried dry extract powdermachine

The dry granulator should be equipped with304Stainless steel platform1Set (including dry granulator, vacuum feeder, total height not exceeding4.5meters), the stainless steel platform should be designed to facilitate equipment operation and maintenance, and include relevant safety protection measures.

The stepping platform and operating platform are made of anti-slip patterned material.304Stainless steel plate, platform column using304Stainless steel square tube (≥100*100); The step height should not exceed175mm, the width is not less than260mmThe length and width of the operating platform should be appropriate to facilitate equipment operation and maintenance; the size and thickness of the processed materials should meet the platform's load-bearing requirements (including the weight of equipment, operators, and maintenance personnel).

The guardrail adopts304Stainless steel square tube welding, height not less than1200mmThe crossbars and vertical posts shall be made of ≥40*40Stainless steel square tube,Inside the vertical rod, use ≥30*30Stainless steel square tube, vertical rod spacing ≤200mmThe dimensions and thickness shall meet the safety protection requirements.

The material of the pressure roller complies withGMPRequirement (to be specified in the technical proposal), Dimensions: φ200×75mmThe roller speed is continuously adjustable (the speed range can accommodate the pressing of different materials); it adopts a reasonable installation and fixation method for easy disassembly and cleaning; it has sufficient strength to resist deformation from extrusion, and must not chemically react with pharmaceuticals, adsorb pharmaceuticals, or release substances into pharmaceuticals.

Request for one set each of fine straight grain, mesh grain, and smooth pressure rollers.

The gap between the pressing rollers should facilitate the extrusion and forming of materials, and the gap should be adjustable (with precision).≥0.1mm), there must be no powder leakage or clogging. The displacement sensor must be from an internationally leading brand.

The pressure roller must be equipped with a doctor blade, and the material must comply with the requirements. GMP Requirements (to be stated in the technical proposal): available in a timely mannerguaRemove the material adhering to the pressure roller and effectively prevent the generation of debris.guaThe knife can be used with straight-grain, mesh-grain, and smooth pressure rollers (if not universally compatible, one set of knives will be provided for each of the three types of rollers).

The pressing roller is cooled by a cooling water system (equipped with an independent external chiller), utilizing a negative pressure water circulation cooling structure. It features internal cooling water channels that ensure the heat generated during rolling is rapidly transferred to the cooling water, effectively preventing thermal deterioration of temperature-sensitive materials. Measures are in place to prevent leakage of the cooling medium.